Publications
Issued Patents
High Efficiency Retroviral Packaging System. M Finer, T Dull, D Farson. United States Patent 5591624.
Method for Production of High Titer Virus and High Efficiency Retroviral Mediated Transduction of Mammalian Cells. M Finer, T Dull, K Zsebo, K Cooke, D Farson. United States Patent 6218187.
Method and Means for Producing High Titer, Safe, Recombinant Lentivirus Vectors. L Naldini, T Dull, D Farson, R Witt. United States Patent 6428953.
Adenovirus E1A/E1B Packaging Cell Line. D Farson, L Tao, Y Li, DC Yu. United States Patent 7074618.
Methods to Express Recombinant Proteins from Lentiviral Vectors. J Fang, K Jooss, A Simmons, D Farson, JJ Qian. United States Patent 7632509.
Edited Papers
Shih, S.J., Miyahshita-Lin, E., Tseng, W.J., Wang, A., Li, J., Yagami, M., Vives, F., Aimi, J., and Lin, A. Use of a bioamplification assay to detect nonselective recombinants and assess the genetic stability of oncolytic adenoviruses. Hum Gen Ther 21, 1707-1721 (2010). DOWNLOAD
Shih, S.J., Yagami, M., Tseng, W.J., and Lin, a. validation of a quantitative method for detection of adenovirus aggregation. BioProcessing Journal 9 Issue 2 (Winter 2010–2011) DOWNLOAD
Published Papers
Farson, D., Tao, L., Ko, D., Li, Q., Brignetti, D., Segawa, K., Mittelstaedt, D., Harding, T., Yu, D.C., and Li, Y. Development of novel E1-complementary cells for adenoviral production free of replication-competent adenovirus. Mol Ther 14, 341-344 (2006). DOWNLOAD
Farson, D., Harding, T., Tao, L., Liu, J., Powell, S., Vimal, Yendluri, S., Koprivnikar, K., V. Ho, K., Twitty, C., Husak, P., Lin, A., Snyder, R. and Donahue, B. Development and characterization of a cell line for large-scale, serum-free production of recombinant adeno-associated viral vectors. J Gene Med 6, 1369-1381 (2004). DOWNLOAD
Farson, D., Witt, R., McGuinness, R., Dull, T., Kelly, M., Song, J, Radeke, R., Bukovsky, A. and Naldini, L. A new-generation stable inducible packaging cell line for lentiviral vectors. Hu Gene Ther 8, 981-997 (2001). DOWNLOAD
Farson, D., McGuinness, R., Dull T., Limoli, K., Lazar, R., Jalali, S., Pennathur-Das, R., Broad, D., and Finer, M. Large-scale manufacturing of safe and efficient retrovirus packaging lines for use in immunotherapy protocols. Gene Med 1, 195-209 (1999). DOWNLOAD
Abstracts
Farson, D., Liu, J., Escarpe, P., Rollence, M., Tao, L., Simmons, A., Fang, J., Yi, S., and Jooss, K. Rapid generation of high-expressing antibody producer clones using a novel technology comprised of a 2A cleavage sequence that allows efficient co-expression of antibody heavy and light chains. World Antibody Congress, June 2006.
Farson, D., Tao, L., Ko, D., Harding, T., Li, Q., Brignetti, D., Yu, D. C., and Li, Y. Development of novel E1-complementary cells for adenoviral production free of replication competent adenovirus. American Society for Gene Therapy, June 2005.
Farson, D,A., Tao, L., Ko, D., Harding, T., Yu, D.C., and Li, Y. A novel adenoviral E1 complementary cell for eliminating replication competent adenovirus (RCA) during viral production. American Society for Gene Therapy, June 2004.
Townsend, K., Chen, Y., Dayao, J., Farson, D., Miller, W.M., Lin, A. Adaptation of a lentiviral vector producer cell line to reduced-serum, suspension culture for large-scale production. American Society for Gene Therapy, June 2004.